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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Loyal employees of this auto services company are rewarded on their 10th anniversary -- and every five years after --with a weekend getaway at a resort in Boca Raton, Fla. (The company is headquartered just 15 minutes away.)
《使女的故事》

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

据Birinyi收集的数据,下面是今年迄今已经获得授权的5大回购。
答:其实我并不怎么关心作品火不火的,就是专注于自己的作品而已。每次我关注的就是要怎样用最好地推进剧情而已。我关注的是行为和故事,不是受欢迎程度。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

在4月24日当天,周某带着农药来到重庆荣昌益民技工学校,并把毒药藏在了桌子下面。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

最近,无人驾驶汽车的新闻屡见报端,它也叫做自动驾驶汽车。谷歌的自动驾驶汽车是此行业的领头羊,已行驶48万千米(30万英里),仅发生过两次交通事故,还都是人为因素造成的。事实上,无人驾驶汽车并不是新奇事物,早在达·芬奇发明以弹簧发条作驱动带内置预设程序的马车时,自动驾驶的概念便名噪一时。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 农房私卖无效 法院强制腾退
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Self-driving cars, selfie sticks, drones, touchscreen devices, e-cigarettes, jetpacks, and many other things seem like fairly modern inventions. Indeed, most of their "inventors" list them as newly invented and even go as far as seeking patents. But the fact is, many of these "inventions" have already been in existence for quite some time. They may have earlier lookalikes that ended up not going into production or that went into limited production due to one reason or another. Some also made it into full production but were recalled due to poor sales.
随着性骚扰丑闻迫使投资者反思他们支持大多由年轻白人男性所创项目的习惯,新的一年硅谷的女性创始人将筹集更多资金。被不光彩传言缠身的一些男性创始人,其初创企业将无法再拿到融资,即使它们是很好的投资项目。
An otherworldly romance between a mysterious aquatic creature and a mute girl, played by Sally Hawkins.
While Insead’s joint programme dropped back into second place, its single-school programme moved up three places to fourth, a place it last occupied in 2011.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Makers of processed food, soda and fast food see markets in the developing world as their greatest growth opportunities. At the same time, obesity rates and weight-related illnesses are on the rise in developing countries. An ongoing series of articles examined the interaction of these two trends, starting with cases in Brazil, Ghana and Colombia. Taken together, these stories reveal “a new global food order, and a new health crisis.”
它会自然生长成模子的形状。
他会在自己的独唱专辑中尝试什么样的歌曲呢:《Sweet Creature》(《可爱的人儿》)和《Ever Since New York》(《自从来到纽约》)是温馨的原声抒情歌曲;而在《Kiwi》(《奇异果》)这首歌中,他大声地炫耀着自己的欢乐;《Two Ghosts》(《两只幽灵》)则是一首为分手而惋惜的歌曲。
美国的排放量在经过了最近几年的持续下降后,提高了2.9%。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

One side of the capsized Eastern Star was rolled above water at 7:30 am Friday, as rescuers worked through the night to right the upturned ship in the Yangtze River. The side that has emerged shows "Eastern Star" in Chinese character on the hull.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Polls indicate that the Dutch election will be extremely tight. Mr Rutte’s centre-right VVD sits atop most polls, just 3 percentage points ahead of the PVV. Most polls show a large percentage of voters remain undecided.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

May the New Year be a time of laughter and real enjoyment for you. Best wishes.
活跃的ETF市场将取决于基于收费的分销网络的发展。富达国际(Fidelity International)亚太区董事总经理陶博宏(Mark Talbot)表示,分销基础设施正抑制零售需求。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

今年最佳的季中交易早已发生了:
Kate Winslet is another Brit who’s opted for the loo for her best actress Academy Award, which she was awarded for her complex role as a concentration camp guard in the 2008 adaptation of Bernhard Schlink’s novel, The Reader.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

凯莎《彩虹》
2014年,演员蒂尔达·斯文顿(Tilda Swinton)在四部电影中戴着假牙:《零点定理》(The Zero Theorem)、《布达佩斯大饭店》、《唯爱永生》(Only Lovers Left Alive),以及奉俊昊导演的《雪国列车》(Snowpiercer)。在最后这部惊悚片中,斯文顿饰演残酷、狡猾的梅森部长(Minister Mason),她戴着一副大大的眼镜,有一口庞大、丑陋的牙齿。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

?根据市长迈克尔?布隆伯格,报道的33个事故有10个发生在纽约,数字还有望上升。纽约的死亡是由于倒下的树木、电击和溺水。
宾夕法尼亚州立大学的气候科学家迈克尔·E·曼恩(Michael E. Mann)在电子邮件中说,“如果不是由于燃烧化石燃料所产生的、导致地球变暖的气体排放越来越多的原因,在上千年史无前例的几十年较暖期间、创纪录地变暖的十年中,看到变暖的又一个记录年度,是非常不可能的。”
New Year's greetings and best wishes!
如果Lloyd Grossman有机会进入奥斯卡得主们的家中,他将会在很多不同的地方看到他们各自的小金人,从高级房产的壁炉台到积尘良久的壁橱深处,都可能看到它的身影。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

最新名单显示香港大学排名第三,澳门大学排名第六。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 水泥业迎史上最严减排标准
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

“他随和、真诚、亲切,”IBM首席执行官罗睿兰(Ginni Rometty)说,并赞赏他“非常本真。这是现代CEO的特质。所见即所得。”
“我都不知道要怎么解释拿了年度风云人物奖之后,还是没有女性杂志和组织支持我的事。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Speculative trading of agricultural commodities has been a feature of the markets’ volatility in 2016, and Rabobank expects the trend to continue.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

值得注意的是,本年度传播假消息之首的网站域名当属“abcnews.com.co.” 在十一月的一次Verge的采访中,伊利诺伊州大学信息科学学院的Nicole A. Cooke教授引用了一个假新闻网站上的消息,这个假新闻网站使用的是危险和普遍的策略,即域名和真网站看上去只有微小的区别。他们让消息源从第一眼看上去具备真实性。管理abcnews.com.co的人告诉华盛顿邮报,他相信他的网站在特朗普大选期间充当了一个重要的因素。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 蒙西“绿色水泥”树行业新标
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

知名安全机构SplashData近日发布2017年最糟糕密码榜单,统计于今年遭泄露的超过500万个密码。“123456”和“password”(密码)再度居首。
在外界看来,中国的经济实力还在从未经历文化大革命的年轻一代中,激发起民族主义情绪。北京方面在对待海上主权争议时的强硬回应,在本已对中国经济实力产生戒心的亚太区加剧了各方对中国军事目标的担心。这也是促使日本决定放松武器出口禁令的原因之一;令中国沮丧的是,其行为还推动邻国支持美国加强自己在亚洲的存在,并使得地区贸易一体化变得复杂。
你要去里约看奥运会吗?你会在安卓或者iOS上装谷歌地图这个应用软件吗?我想你已经有了答案了。
6. Lighting

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

这是智慧的时代,也是愚蠢的时代……
They're developing a core and sorting through roles. Because they're the Lakers, there remains the possibility that a solid free agent or two will look their way.
没有卡戴珊获奖的不文明大奖能算完整吗?
adj. 独一无二的,独特的,稀罕的
如果说2017年是政策制定者们开始担心“无保障无产阶级”(precariat)人数增长的一年,那么2018年将是他们尝试为此做些什么的一年。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

汉娜库赫勒(Hannah Kuchler)是驻旧金山记者
n. (准备好演出的)节目,保留剧目,(计算机的)指令表

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

不过,在长达四小时的马拉松般的颁奖典礼中,《月光男孩》所获奖项一度与《爱乐之城》并驾齐驱。巴里?詹金斯(Barry Jenkins,文首图中)和塔雷尔?阿尔文?麦克拉尼(Tarell Alvin McCraney,文首图右)获得了最佳改编剧本奖。马赫沙拉?阿里(Mahershala Ali)获得最佳男配角奖,这是美国穆斯林男演员首位获得奥斯卡奖。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

这些表情包恶搞的话题涉及恋童癖、虐待儿童、性侵害以及纳粹大屠杀。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

在收入最高的大学毕业生中,科学和工程领域占据了主导地位,其中软件工程、生物科学和电子信息工程是最赚钱的专业。
GoldSeek.com的这个标题发出了红色警报。在评估另外20名专家跟踪的20种周期之后,它总结道:“很多周期表明股市的调整或崩溃已经临近……未雨绸缪是很重要的。在‘窗口’关闭之前,你仍有一些时间!”
单词portion 联想记忆:
Quiz

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

This is all bad news for investors, just as America's 30-year bond bull is ending.
The emotions were far more visceral and less attractive.
失宠行业
1. glitterati / n . 知名人 士,国际上层社会人士。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

“I don’t think there are any companies that have survived big assaults from two of the biggest beasts in the hedge fund jungle,” says Ms Simpson of Calpers. “He is cool, calm and collected — the corporate exemplar of ‘Keep calm and carry on’.”
China's newly issued lunar New Year monkey stamps marking 2016, another Year of the Monkey, also designed by Huang and each with a face value of 1.20 yuan, have attracted much attention, with collectors lining up outside post offices ahead of their release.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Hillary stays on: Clinton’s CV is chock full of firsts: The only first lady to become a U.S. senator turned viable presidential candidate turned secretary of state. Now a private citizen, she continues to be one of the most watched and listened-to women on the planet. All bets on that she will be the 2016 Democratic presidential candidate and the free world’s presumptive next leader. She’s done little to quiet the chatter, including hitting the speaking circuit last month at an estimated $200,000 fee per event and inking a reported $14 million book deal.
小说作者安东尼·赫洛维兹(Anthony Horowitz)透露,新书《Trigger Mortis》为现代读者作了改动,包含反对吸烟的信息,而且首次有一位“直言不讳”的同性恋朋友出场。
All held together with imported white stilton cheese, the flakes are interspersed on the pie with dollops of Ossetra caviar from the Caspian Sea as well as truffles and Fois Gras from France.
rid笑+ic+ulous多…的→多笑的→可笑的
单词triangle 联想记忆:

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

8.鲜花往往不属于赏花人,而属于牛粪。
Two colors! It may not sound revolutionary, but everything is relative. And know this: It’s not about indecision, but social progress. That’s Pantone’s position, anyway.
We also do not want any trade war with others and we have stuck to reform of the yuan's exchange rate formation mechanism to keep it basically stable at reasonable and equilibrium levels.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 涂料市场今后将会如何发展
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

举例来说,新浪微博就一直提供推特所不具备的一些功能,尤其是评论功能,让众多用户得以在别人发表的微博下发表自己的见解。拥有逾7亿用户的腾讯QQ即时信息服务也有众多附加功能,比如可以让用户改换形象的“皮肤”,同时QQ还是腾讯为其他产品和服务做广告的渠道。新浪拒绝置评。
过去二十多年间,我一直在写关于亚洲崛起及其推动力量的文章。东亚各国领导人之间有一个了不起的共识:亚洲需要利用当前的机会之窗,把重点放在经济发展和增长上。战争是发展的最大阻碍。如果亚洲人真的愚蠢,他们或会卷入这样的战争,破坏自己巨大的发展前景。大多数亚洲国家(除了朝鲜)的领导人,都很明白战争的危险。因此,虽然这一地区会出现局势紧张和对抗,但无论在2014年还是2015年都不会爆发战争。随着2015年缓缓展开,我想鼓励所有西方学者根据亚洲本身的情况理解亚洲的根本发展动力,而非将理解建立在西方先入之见的基础上。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Cliff Stevenson, an anti-dumping expert who publishes the report based on data filed with the WTO, said the surge in US cases was driven largely by the steel industry. The increase also represented the range of countries from China to Australia, the UK and the Netherlands against which US companies were willing to file anti-dumping complaints.
DNA from the bones matched that of descendants of the king's sister, while the skeleton had the twisted spine and battle injuries consistent with contemporary accounts, said researchers from the University of Leicester.
Company: Project Frog

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Mayweather Jnr - who is capable of demanding pound 70 million a fight - fell to 16th. He pocketed pound 20 million in ring fees with an additional pound 5 million coming mostly from his clothing brand TMT, The Money Team.
2、Lying
but that was markedly lower than the previous month’s rise of 8.2 per cent.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

“如果贷款机构在市场繁荣时过于乐观,而在市场下行时过于悲观,这或许是当局设定保守的资本金要求的一个最好理由,”他说。“加大折幅可能会抑制最初的涨幅,但当市场转向,它们也能抑制随后的跌幅。”

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

China does not want to see a trade war between the US and China. That would not make our trade fairer and cause loss for the both sides.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

在星期六晚上他们再次献唱《悲惨世界》原声《Stars》。
Bill Gates topped the list of the world's richest billionaires for the 17th time in 22 years, it has been revealed.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 北京将会限制“企业购房”?
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

14. Google Calendar
It is not hard to think of recent examples, from Hugo Chávez to Viktor Orban and Vladimir Putin.
A teenage student in Southwest China's Chongqing Municipality has been sentenced to one year in jail after trying to poison fellow students for being too noisy in class, local media reported last Wednesday.
朱克斯提醒,我们目前正处于第四次超级大泡沫之中,它是美联储在保守经济学兴起以来的30年时间里吹起来的。他将这个泡沫称为“暂时没有名字的泡沫”(Bubble With No Name Yet)。好,大家来给这个新泡沫命名吧。但不管你叫它什么,都要快点起名,因为它马上就要爆了,就像过去30年相继破灭的亚洲泡沫、互联网泡沫和信贷泡沫一样。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

“Yao represents the new wave of wealth creation by financial investments in China,” said Rupert Hoogewerf, who compiles the annual list.
时间:2011-06-02 编辑:beck

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

The No. 1 thing in job security is your relationship with your boss. Even if he says, "I'm sorry I really wanted to keep you, but they made me lay you off," that's almost never true. He probably made that decision.
Lecent was with an unknown number of other youth when she was killed by a single bullet inside a home in a public-housing complex near Martin Grove Rd. and Finch Ave W.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

《老友记》中没有露骨的内容、不干净的台词或是黄段子,但它的幽默感却丝毫不减,为这个电视剧总喜欢裹挟着露骨内容的年代带来一阵清新之风。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

如果你认为一开始准确判断应增持和减持哪些行业的股票是件难事,在年内不断调整投资组合更是难上加难。11月,野村证券一位定量分析师向《巴伦周刊》表示:“行业领军者每个月都在变换,其变化速度之快,在股市数十年未见。即便你选对了某行业的个股,由于市场环境瞬息万变,业绩也根本无法持续。”
考试之前,网友通过社交软件,将考试中将要出现的问题和答案截图发布出来。
自从18个月前在亚洲设立业务以来,克拉布一直没有涉足香港房地产市场,因为他表示,价格太高了,可担负性太差。
陈女士说:“所有这些搜索项综合反映了2010年的许多方面,还反映了这一年政治和技术领域的变革。”

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 大众消费高要求 创意家居受青睐
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

People (read: your boss) will notice if you go from sporting a uniform of jeans and a T-shirt to showing up in a tailored suit on interview day. This is all the more reason to take the day off from work to interview, but if you don't, dress as usual at the office. And then, Foss says, "leave the premises, and stop in a McDonald's parking lot on the way to the interview to change."
根据一项针对技术发展的国家规划,到2020年时,研发经费的目标是要达到GDP的2.5%。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

智能酒瓶
16. Zapier
Captivating, funny and possessed of a surprise-filled zig-zag structure that makes it impossible to anticipate where it's headed, this is a deeply humane film that, like the best Hollywood classics, feels both entirely of its moment and timeless.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

税:每年大约41684美元(约26.7万元)
That price looks excellent given that Tucker should fit more neatly in a three-and-d role than Ross, Sullinger is a total non-factor, and the Raptors kept their own 2017 first-round pick.
This is a thorny issue that’s unique to messaging apps. We expect ads to live alongside content we consume. We don’t expect them to crop up in our one-on-one communications. “The last thing you want in a personal conversation is a banner ad or pop-up that interrupts that,” Wray says. “It might work with more impersonal networks, but specifically within messaging, people hate traditional ads.”

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

户外空间:这栋房屋占地面积五分之一英亩(约809平方米)由纽约公司Landgarden负责景观设计。房屋前面的这座日式花园中采用了当地的植物。这栋房屋后面还有一处露台和院子,那里还有一座日式花园。
o Battery power may turn out to be a transition technology. Cost reductions have been slow in coming, and Tesla needs a 30% improvement in order to build the $35,000 Model 3 it has promised for 2017. Toyota’s recent move was eye-opening. It is allowing a battery-supply deal with Tesla to expire and instead will redouble its work on hydrogen fuel cells. The cost of fuel cells is coming down faster than batteries and fuel cell proponents believe drivers will prefer a relatively rapid refuel with hydrogen to waiting hours to recharge their batteries.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

My Dear Wife
Barney Thompson is legal correspondent
可口可乐表示,中国消费放缓打击了销售额,而较为疲弱的需求正迫使其降低库存。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

New year’s events can be anticlimactic. Not so in China where stock markets began 2016 with enough excitement to make traders choke on their bubbles: Shanghai stocks dropped 7 per cent on Monday, Shenzhen more than 8 per cent. It could have been worse. A new mechanism that suspends trading after a drop of 7 per cent halted play early — in this instance, by an hour and a half.
201312/270511.shtml重点单词

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

['rep?twɑ:]
第二步 重复标志性动作
"Why do the slaves all dress in white and look like fairies in this drama? Plus they even ran faster than horses. Is it reasonable?" user Shiweitian said.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Hartz started Eventbrite, an online ticketing platform, with her now-husband Kevin in 2006. Since its founding, the company has raised $140 million from firms like Sequoia Capital and Tiger Global Management and reached $2 billion in gross ticket sales this September. Entrepreneurship forced Hartz to appreciate candid and collaborative conversations. "I had to learn how to ask for help," she says. "Everyone always thinks it's brave to go out alone, but I think it's even braver to put yourself out there in front of others, and to figure out how to work together."

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

尤吉利时机恰当和思虑周密的举动应该能扭转猛龙下滑的颓势。
退出单向乐队之后,哈里·斯泰尔斯可以去自己想去的任何地方。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Still relevant
Columbia Pictures克里斯蒂安?贝尔、艾米?亚当斯和布莱德利?库珀在电影《美国骗局》中早在1月份闹片荒的时候,人们不会想到今年会迎来如此多好电影。不仅如此,有几部影片甚至达到了被我们在心目中理想化了的那些老电影的水准。今年有两部电影脱颍而出。纯娱乐片方面,赢家显然是《美国骗局》(American Hustle),这部由大卫?欧?拉塞尔(David O. Russell)执导的影片讲述了上个世纪七十年代的行骗高手和他们的微妙骗术的故事,幽默诙谐,令人捧腹。而从创新角度看,《地心引力》(Gravity)的全新拍摄技术给观众带来了新的观影体验。人们普遍认为《美国骗局》无可挑剔,这部疯狂喜剧片是一部时代佳作。我个人则认为,《地心引力》是今年的最佳影片。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

1. How to make pancakes
利拉詹纳

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Enrollment: 511
如果这届奥斯卡最佳影片的提名数有9或10部电影的话,那么《逃出绝命镇》能占一个。乔登?皮尔的剧本应该一定会被提名。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

n. [计]定序;排序;订购 v. 命令;指挥;订购(o

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

The Republican candidate appeared unsure at times and occasionally stumbled over his lines as if struggling to remember his briefing notes. He began sweating as Obama, aggressive from the start, got the better of him during exchanges on Iran, Iraq and Russia as well as on US military spending.
当芬兰程序员Jerry Jalava 2008年遇到车祸,他面临双重悲剧。首先,他失去了他的手指,对于靠打字生存的人来说是个大问题。其次,他必须跟一个幽默感过剩的医疗小组打交道。了解了他的遭遇后,一位外科医生竟然提议Jalava应该出门去买个“USB手指驱动器”。
The collaboration with business is important, adds Teach First, not just for the funding but to help schools equip students with more of the skills required by modern employers.
While D'Aloisio spends 80 percent of his work time retooling and improving Summly (which has already been integrated into Yahoo!'s iPhone app), the other 20 percent is devoted to imagining the expansive challenges he'll take on next. He predicts there will be summarization programs that do for video what Summly does for the written word. He has grand thoughts about using technology to aid learning and would like to help fellow autodidacts while disrupting the old educational models.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

谢丽尔·布恩·艾萨克斯,学院理事会主席

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

添加一些个性元素。把自己家人的照片或东西放在桌子上可以提醒你为什么你要努力工作。
这部由塞巴斯蒂安.马拉比(Sebastian Mallaby)所著的《知者:格林斯潘传》(The Man Who Knew),是这项奖金额为3万英镑的奖项的第12位获奖者。该奖项奖励的是年度“最令人瞩目和愉悦的”图书。
2.别迷恋哥,哥只是个传说。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The third gunman, Amedy Coulibaly, who stormed a kosher supermarket on Friday,never left for such training, said Valls.
会。供应中断和地缘政治风险因素很可能会持续出现,同时伴随着全球生产商限产。但价格能否保持在70美元或以上水平取决于:在美国页岩油供应不断增长的情况下,俄罗斯是否愿意继续支持沙特阿拉伯牵头的限产努力。参与限产的其他国家也需要继续坚定地遵守协议——随着各国政府受益于油价上涨,继续遵守协议的动力将越来越小。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Rounding out our top five is Sandra Bullock, one of only two women on our list (the other is Jennifer Lawrence in 10th place). Bullock had two big hits this year in two very different genres: Gravity was a tense thriller that will likely earn her another Oscar nomination, while The Heat was a cop comedy that kicked butt at the box office, bringing in $230 million globally.
单词fare 联想记忆:

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 建材企业的日子也不好过
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

'My first duty, my first responsibility was to be true to the original feel of the book, to be true to Ian Fleming: his creation, his world and his ideas.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

We will deepen rural reform.
陶博宏指出,日本监管机构正在鼓励基于收费的销售模式,出台了新的受信规则和其他措施,这些举措将会增强ETF的低成本吸引力。
2.人工眼睛

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

最佳迷你剧集/电影类编剧:D?V?蒂文森斯(D.V. DeVincentis),《美国罪案故事:公诉辛普森》,“玛西亚,玛西亚,玛西亚” (The People v. O. J. Simpson: American Crime Story, "Marcia, Marcia, Marcia")
凯特温丝莱特凭借她在电影《乔布斯》中扮演的乔安娜霍夫曼一角斩获金球奖最佳女配角奖项。当她听到自己获奖时,她目瞪口呆地坐在椅子上不敢相信。
C罗巨无霸般的收入主要来源于两部分。一部分是他效力于西班牙豪门皇家马德里挣得的令人眼红的3850万英镑的年薪。另一部分来源于他为耐克、豪雅表和营养品公司康宝莱代言带来的总计2200万英镑的代言费。
More than 430,000 students from 1,767 universities in 31 provinces, municipalities and autonomous regions across China were surveyed. Of the respondents, 89.2% had considered starting a business, with 18.2% reporting firm intentions to do so.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

恭祝健康、幸运,新年快乐。
Trailing China in 2015 was the UK with $1.9 billion, Japan, $1.8 billion, India, $1.6 billion, and South Korea, $1.5 billion.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

流通量小也助长了给猴年邮票创纪录的价格。在1980年,只有500万“金猴”枚邮票发行,所以现在非常罕见。
1.《廷巴克图》,导演:阿伯德拉马纳·希萨柯(Abderrahmane Sissako)。
According to exam questions and some test-takers' feedback posted online after the exam, the difficulty of the questions was moderate and hot political and social issues, such as the Long March rockets, China's foreign affairs, the Yutu lunar rover and entrepreneurial efforts by college students, were mentioned.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

2015年FT/麦肯锡最佳商业图书奖(2015 Financial Times and McKinsey Business Book of the Year)的获奖作品是《机器人的崛起:大规模失业的威胁与科技》(The Rise of the Robots: Technology and the Threat of Mass Unemployment),这本书对工作自动化的未来做出了令人不安和常常令人消沉的分析。
10. The difference between a lie and a promise is that the believer of a lie is the listener and the believer of a promise is the speaker.

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