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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

During the summers, Good Humor ice cream trucks visit the company's campuses every other Friday during lunchtime. In the fall, cider and doughnuts are served twice a month, mid-morning.
The country has rolled out measures to promote new-energy vehicles, including tax exemptions, subsidies for car purchases and a requirement for government departments to buy more new-energy cars.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

报名窗口将于周六关闭,报名成功者须参加11月29号的2016年国家公务员考试,考试通过后才可以参加明年3月的面试。
[?'k?mpli?t]

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Rankings for Greece, Italy, Portugal and Spain fell dramatically because of the impact of the eurozone crisis, while Egypt, Myanmar and Saudi Arabia registered large falls in the wake of recent political and civil turmoil.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

scary puppy like head tilts and glares

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

In the true-crime drama “Foxcatcher,” the actor Steve Carell, best known for comedy, loses himself behind a prosthetic facade in portraying the multimillionaire John E. du Pont. The standout in the makeup package is the beaklike nose he sports.
年龄:39岁
已经60岁的微软老大净资产达到750亿美元,尽管比起2015年缩水了42亿美元,却仍足以傲视群雄。自2014年超越墨西哥首富卡洛斯·斯利姆·埃卢以来,盖茨实现了福布斯富豪榜榜首三连庄。
We first see the hair of Anna Morales (Jessica Chastain) during the opening credits of “A Most Violent Year.” She’s at her makeup mirror.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

10. 《66》(Sixty Six)。刘易斯·卡尔(Lewis Klahr)把数码短片精彩地汇集在一起,以一种英雄气概的方式复制流行文化,它只在MoMA上映过一晚。但他的作品也在洛杉矶和旧金山等城市上映,所以如果你住在附近,可以去看他的下一次展映。
3所在这份榜单上叱咤多年的重量级学府——哈佛商学院(HBS)、伦敦商学院(LBS)和麻省理工斯隆管理学院(MIT Sloan School of Management)的排名下滑。哈佛商学院的排名下降两个位次,今年排在第四,这是这所位于波士顿的学府9年来首次跌出前三甲。伦敦商学院下滑3个位次,排在第六,为14年来最低。麻省理工斯隆管理学院的排名下滑至第13位,为10年来首次跌出前10。
8.Form or Join a Study Group
连平说道:“在2017年的低基准上,今年CPI可能会以一个更快的速度上涨,但在需求稳定、货币环境紧张的背景下,不会出现明显的通胀压力。”

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Exports to the EU, Japan and Hong Kong — which serves as a transit point for exports to many other parts of the world — fell by 4.1 per cent, 9.5 per cent and 12.2 per cent respectively.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

大部分岛主为意在开发旅游业的企业,但也有私人岛主,他们买岛则是为了在岛上建私人会所招待朋友。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

PRICE PER SQUARE FOOT: $667
如果陆金所成功完成此轮融资,将可凸显出该行业今年以来增长有多快。该公司刚在4月融资5亿美元,公司估值在当时达到100亿美元。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Their inclusion has come at the expense mainly of European companies, signalling the shift in economic power towards the east. There is only one Indian brand in the top 100 ranking — HDFC Bank. Russian, Mexican and Brazilian brands have fallen out of the ranking in the past few years — a sober reflection of the changing fortunes of these emerging markets.
So, before the world gets the better of you and slaps a title on your forehead, create a unique manifesto of what you think you are.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

5. “In Jackson Heights” The latest from the brilliant Frederick Wiseman has a three-hour-plus running time; maybe this explains why once again the dunderheads at the Academy didn’t put him in contention.
Remedy: Make a budget. If you don’t know how much money you need to live the lifestyle you feel comfortable with, you can’t accurately project whether switching jobs for a $10K pay bump is actually a good deal. Making a pros and cons list when comparing your current job with a new opportunity is also helpful. If the only advantage a job offers is a bigger pay check, you can weigh that against longer hours, a more onerous commute and increased reporting responsibilities. Keep in mind that research shows that increases in happiness based on earnings peak at about $75K. Incomes above this level don’t increase your feeling of well-being on a day-to-day basis. So, if you think a jump up to $85 or $90K will make you feel less morose when your alarm goes off, you might want to look at addressing some of the non-monetary factors in your life that are contributing to your dissatisfaction.

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 坐地收租家居卖场老路走不通了
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

据中国保监会(Insurance Regulatory Commission)公布数字,上半年利润总额1055.86亿元人民币(合159亿美元),同比减少1241.99亿元人民币,下降54.05%。
The hunt for his body began in earnest in 2012 when archaeologists working on historical accounts and geographical clues started to dig beneath the municipal carpark on the spot where Greyfriars was, and found the skeleton.
Mr Cook must balance that with the secrecy that surrounds its product development. Already, there are whispers on Apple’s campus about another secret project, on the scale of the iPhone or Watch, which is pulling in talent from across Cupertino.
The Crown

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 租户人身安全亟须立法明确保障
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

The reality turned out to be tougher than he imagined. “I saw it as a two-year opportunity,” says Mr Ravenscroft. “The grinding reality is that it’s a slog.” Moreover, his mentor worked at Lehman Brothers, the bank that collapsed in 2008. “It wasn’t quite as long a mentoring relationship as I’d hoped,” he laughs.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 租户人身安全亟须立法明确保障
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

要让消费者有更多选择,从中受惠,更重要的是让我们的企业下决心,通过发扬工匠精神,使自己的产品赢得消费者的信赖。
用走私野生动物制成的商品到哪里去了?

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 4月北京房租价格微涨
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

据报道显示,一些贷款机构一直在利用借贷宝向女大学生提供高息贷款,条件是贷款人必须提供持有身份证拍摄的裸照作为抵押。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

DeMarcus Cousins, Serge Ibaka and Lou Williams were all dealt in advance of Thursday's 3 p.m. ET deadline, leaving role players like Taj Gibson and P.J. Tucker as the biggest names to move right before the buzzer.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

接受一份谋生型的工作有两个弊端。这样做会让你在求职中分心,而且潜在雇主对你以前的专业形象会有所怀疑。
One difficulty in assessing the potential for ETFs in Asia, say experts at the largest asset management houses, is both the disproportionate size of the Japanese market within the region and the role played by the Bank of Japan, which distorts the market as it buys ¥6tn ($54bn) of ETFs a year.
“你美丽得如此不真实,我的视线无法从你身上移开”,这爱意满满的歌声使金发女郎笑得合不拢嘴,同时她也拿出手机记录下了这美妙的一刻。
国际消费类电子产品展

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

In contrast, the nation witnessed a tumbling trend for minivans, whose volume totaled 71,300 units, a 31 percent drop year-on-year.
[f]
The International Organization for Migration says the number of migrants and refugees entering Europe in 2015 has gone over the one million mark, the largest influx of its kind since the end of World War Two.
1. Technausea.
伦敦商学院课程的一个主要优势是学员来自地域广泛的不同国家。其2015年MBA课程学员的90%来自海外,来自大约60个不同国家。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Lots of managers recalled extreme etiquette errors. The applicant
The first time an influenza virus was found to be transmitted directly from birds to people, with infections linked to exposure to poultry markets. Six people in Hong Kong died. This virus was different because it moved directly from chickens to people, rather than having been altered by infecting pigs as an intermediate host. In addition, many of the most severe illnesses occurred in young adults similar to illnesses caused by the 1918 Spanish flu virus.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

节目9 相声《这事儿不赖我》,曹云金 刘云天

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

然而,北方高等商学院毕业生的国际化流动程度最高,2014届毕业生有85%曾在国外工作。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Wishing you happiness during the holidays and throughout the New Year.
中央纪委国际合作局局长腊翊凡表示:“在中共中央的领导下,我们将扩大与有关国家的司法合作,使腐败的外逃人员不存在“避罪天堂”。
继去年10月被《时尚先生》杂志评为“最性感在世女性”、上月被《Details》杂志评为“最性感明星”后,这位美丽动人29岁女郎又得到一个荣誉称号:《男人装》杂志评选的“2013年最性感女性”,她打败了在榜上的其他99位女性和不计其数的未上榜女性。
此外,她还指出同工同酬的问题。她表示这不仅仅是女性的问题,这实际影响到每一个人。希拉里表示:"如果你有妻子,母亲,姐妹,女儿,她们在工作中没有被公平对待,那么整个家庭都会为此受影响。"

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

[.reidi'ein]
Walt Disney Pictures and Lucasfilm have promised a Star Wars film every winter after the release of Star Wars: The Force Awakens. These movies will be spin-offs to the main films.
报告指出,2016年中国网民数量增加了4299万人,同比去年增长6.2个百分点,而网民总人数占到了中国总人口的53.2%。
['trit?bl]

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Jia Yongsheng general director of the demolition company told China's state TV channel CCTV: 'For this kind of large-scale blasting demolition conducted in the downtown area we not only need to guarantee the demolition result but also strictly control the adverse effects of blasting.'
It seems safe to predict lots more noise and very little progress for the rest of 2017. And that will continue to be a damaging combination for business and the UK economy.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 资本“转战”:从炒房价到炒房租
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The issues addressed in friends — relationships, careers, and friendship — continue to be relevant to today’s youth.
5. Gay Marriage
5、低效的邮件沟通
The cyclical theory depends on a dearth of new investment creating a supply crunch in two, three or five years. A lot of projects are being postponed but postponement is no more than a signal to project managers to find a way of cutting costs. Many are doing exactly that.
Companies are always looking to save money, and outsourcing some roles to freelancers can help. Virtual assistants can perform many of the duties of full-time staffers, but with less commitment. These workers could help expand a business, or just encourage things to run more smoothly.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Winners: Mavericks
Song “Happiness” (Mao A’Min)
Company: Binary Group

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Set between the events of Star Wars Episode III and IV, Rogue One will most likely be about bounty hunters who set out to steal the Death Star plans. We're not exactly sure of the plot.
定义自己

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

如果你是一名创业家,那么未来永远是光明的,基于传统服务的数字化来创立新企业的机会简直取之不尽。
“这可以归结为3个问题:怎样推动平台不断升级,怎样继续强化团队,怎样打造与合作伙伴的一系列联盟,以加速自身成长?”凯斯表示。
要让产品显得很“酷”并不是唯一的目的。科技行业如果想让我们身体的更多部位连上网络,那么安全问题和隐私问题,尤其是顾客数据管理问题,依旧需要慎重考虑。正如《经济学人》(The Economist)所说,蓬勃发展的传感器的魅力,以及可穿戴设备的算法,分散了人们对于其他要素的关注。这些关键的其它要素包括:“标准、互通性、一体化、数据管理”,以及“知识产权、执行标准”。对国家安全局(National Security Administration)而言,这些技术发展都必须以网络安全为前提。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

台风哈维
con全部+serve保持+ative→保守的
"Some geniuses in the internet industry created miracles, but that does not tell the whole story," said Chen. "Business has its own rules. Before you start up, you have to know how to produce products, how to sell them, how to manage a company. Those lessons you cannot expect a fresh graduate to know."

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Meanwhile, a salesman from online travel company Tuniu Corp told the Financial Times that it had on Friday “removed all tours to South Korea due to the Thaad issue”. A search for South Korean tours on the website returns the message: “Sorry, we have not found a relevant product.”

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

《橘色》,导演:肖恩·贝克(Sean Baker)。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 上海多措并举筹措租赁房源
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

年龄:53岁
Plum Alley:

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Let us look at what lies ahead for the rest of 2017 in trade:
To make a long story short, the Seppenwolde group went bankrupt shortly after Christmas of 1772. The disaster was a top story in Dutch newspapers. It ruined some of Amsterdam’s merchants and bankers. To prevent a general credit collapse, the city of Amsterdam stepped in temporarily as a lender of last resort. Sound familiar?
上榜的12所美国学院平均而言是性别比例最为平衡的,女性学员比例为48%。
Lorde, 'Melodrama'

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

The first thing you must understand about personality types is that they have nothing to do with genes. This means that if you have a Type D personality then this doesn't mean that you can't change it. Also, the quiz doesn't mean that the result of the quiz determines your destiny. According to psychology, any personality trait can be changed.
[ri'li:s]

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

约翰奥瑟兹(John Authers)
McGowan was born into the polygamous Children of God Cult and ran away from home in her teens.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

单词fare 联想记忆:

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 石材进口报关所需资料流程及费用
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

人类在过去50年的平均寿命比人类存在的20万年中的平均寿命要长的多。目前,人类的平均寿命是70岁,1950年的平均寿命是47岁,两者存在很大的差异。
2. Worldwide Murders
部分在企业界的资助下,该机构将一流毕业生派到面向低收入社区的学校至少两年时间,而且也完全知道,其中许多人将会在这一时期结束后不再从事教学工作。
人们对于可穿戴设备销量的估计各不相同。研究公司IDC认为,这类设备今年的销量将超过1,900万件量,达到去年的三倍以上。到2018年,它的销量将会达到1.119亿件。瑞士信贷(Credit Suisse)预计,在接下来的2-4年中,这个行业的价值将会高达300亿至500亿美元。不过,在这一切实现之前,这个方兴未艾的市场需要摆脱人们对于“穿戴这种设备就是出丑”的成见。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

“…brought his dog.”
不像这篇文章中其他的人造物品,人工胰腺并不处于前期研究阶段,这个装置确实存在,而且在今年9月份得到了FDA的销售许可

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The data measure how successful alumni have been in their career in terms of salary, seniority and achievements since graduating.
2017已经是詹姆斯在联盟中的第十四个赛季,但他的场均助攻和篮板竟然还创下了职业新高。在这个赛季的前两个月里,他拿出了整个职业生涯最好的三分表现,但鉴于这已经被各方专家们讨论和剖析,并且被媒体广泛的报道了,我在这里就不加赘述了。
外部事件的影响。《消费者报告》(Consumer Reports)杂志曾经对Model S大加吹捧,但最近该杂志也报道了它的一些常见故障,包括门把手失效,中控触屏白屏,导致车内大部分功能不能使用等等。汽车网站Edmunds.com也找了Model S的麻烦。更多此类报告无疑会影响特斯拉到目前为止非常正面的声誉。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

5Japan
根据世界黄金协会(World Gold Council)的数据,自2008年以来全球黄金供应每年都增长,这一增长在去年陷入停滞。作为世界最大的黄金生产国,去年中国的黄金供应创纪录地下降9%,这是自1980年来中国的黄金产出第二次下降。
Mayweather Jnr - who is capable of demanding pound 70 million a fight - fell to 16th. He pocketed pound 20 million in ring fees with an additional pound 5 million coming mostly from his clothing brand TMT, The Money Team.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Bank of China posted earnings per share of Rmb0.56, down from Rmb0.61, and a pre-tax dividend per share of Rmb0.175, down from Rmb0.19 last year.
When reflecting on the year in film, moviegoers often remember strong performances, or they might consider how a movie worked as a narrative, the emotions it evoked, what chances it took.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 三四线城市将成橱柜企业布局方向
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

福布斯杂志称,26岁的劳伦斯能排名榜首,大部分得益于从《饥饿游戏》系列影片的最后一部中分得的收入,以及从她参与拍摄的即将上映的太空探险影片《乘客》中所得的一大笔预付费。
杜阿·里帕《杜阿·里帕》
Zheng Gang, a member of the CPPCC National Committee and deputy mayor of Danzhou city, Hainan province.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 阿里巴巴飞利浦达成智能家居合作
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

That deceleration could prove a spoiler to broader growth if it continues apace, as observers have attributed sustained activity growth among manufacturers to stronger domestic demand.
许多老板都会对自己的员工负责,但是优秀的老板也会对他们自己的行为负责。这意味着他们同样会遵守为员工们设置的指导原则,并为团队的成功和失败负责任。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

The Wizards need to surge ASAP if they want to stay in this. We saw what happened last year when they waited too long to get it together.
The fall in profits in December highlights the challenges facing an industrial sector racked by overcapacity and falling prices, adding to pressure on authorities to loosen monetary policy and boost infrastructure spending to cushion the slowdown.
中国信息通信研究院的报告称,2016年国产手机出货量达4.98亿部,占国内手机总出货量的88.9%。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

根据周一发布的年度调查报告,如今实现澳大利亚梦的成本急剧上升,悉尼和墨尔本超过大多数欧美城市,跻身世界最贵城市前五名。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

As if 2016 hadn’t been hard enough for China’s workforce, an annual survey has revealed that more than half of the country’s white-collar employees got no year-end bonus ahead of the upcoming (and costly) lunar new year holiday.
sen年老+ior表形容词,“较…的”→年长的

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 谁来赋予照明的“灵魂”?
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

达成一个全球性气候协议的下一次大尝试,将是在来自世界各地的谈判代表今年12月聚集巴黎的时候。气候变化问题的政治活动人士上周五不失时机地引用2014年的温度记录为证,表明采取强有力行动的必要性。
大力优化外商投资环境。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The actor - who is heavily tipped for his first Oscar this year - won the gong for best actor in a film drama for his role in The Revenant, beating rivals including Eddie Redmayne who was nominated for The Danish Girl.
新兴市场吸收的外国投资已降至金融危机以来最低水平,投资者准备迎接美国近10年来首次加息的冲击波。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

国家统计局最近开始跟踪研究的大城市的房价数据就支持这种可能性。
The leadership changes across the industry will be of particular interest to female consulting professionals, given none of these firms have ever been run by a woman. Consulting firms are vocal proponents of the business case for improved gender diversity at the top of large companies. It will be interesting to see if any of them decide to practice what they preach.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

adj. 商业的

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

8. Ford Motor
The 2014 ranking of 100 programmes for working senior executives is headed by Trium, runby HEC Paris, the London School of Economics and Stern School of Business at New York University. The top five places continue to be dominated by intercontinental EMBAs.
你可以在AskMen.com网站上看到完整榜单。以下是最性感女人前十名:
美国

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 珠三角家居建材企业面临大洗牌
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

单词associate 联想记忆:
单词statement 联想记忆:
Stand: Apple CEO Tim Cook fought for workplace protection for the LGBT community

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

该数据突显出,某些工业部门对他们认为来自中国对手的不公平竞争感到日益担忧。
The Internet has flattened the world, and Facebook has banded us together as one big family. Our grandfathers inherited regions, my generation inherited nations, you have inherited the world. You are now only 4.74 people away from any human being and an average of two days away from any inhabited corner of the world. So travel. Africa, Europe, India, China or Brazil, go where you can learn the most, embrace what can teach you the most.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

It was also the "most liked" tweet of the year, with 4.59 million likes.
Kobe Bryant

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 成渝城市群:双向合力共发展
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

不错,2014年完全是一场灾难,只等着引爆。在《年内股市崩盘的概率有多大?》(Doomsday poll: 87% risk of stock crash by year-end)一文中,我们分析了今年年初以来的10大崩盘征兆。之后,我们又不断发现了更多新的妖魔。它们有如嘀嗒作响的定时炸弹,来自国会、最高法院、性问题、碳排放、石油巨头、国家安全局(NSA)、国税局(IRS)、茶党式财政紧缩。接踵而至,让人无法招架。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

However the prolonged period of contraction fits with the overall pattern of the slowing Chinese economy.
除了众多受过教育的劳动力可供选择,企业也被亚利桑那州的亲商监管环境所吸引,在莫卡特斯中心(Mercatus Center)发布的美国50个州商业自由度排行榜上,亚利桑那州排名第13位。这项研究援引亚利桑那州的劳动权利法、责任法和土地征用权改革作为有利条件。
Talented getaway driver Baby (Ansel Elgort) relies on the beat of his personal soundtrack to be the best in the game. After meeting the woman (Lily James) of his dreams, he sees a chance to ditch his shady lifestyle and make a clean break. Coerced into working for a crime boss (Kevin Spacey), Baby must face the music as a doomed heist threatens his life, love and freedom.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

涨幅放慢也与房地产投资变化趋势吻合。上月,一二线城市的限购措施对房地产投资造成了(些许)冲击,全国范围内的房产成交量和成交金额的增速也有所减缓。
There’s no arguing with that one. From bathroom signs to fashion runways, the gender lines have been blurring at an ever-faster pace. It’s about time we ended ye olde pink/blue, girl/boy stereotype divide.
声明中说:“我们真诚地向《月光男孩》剧组、《爱乐之城》剧组、沃伦?比蒂、费?唐纳薇和奥斯卡颁奖礼观众致歉,因为在宣布最佳影片环节中我们出了纰漏。”
几十年来,史泰龙塑造的这个弱者形象一直在鼓舞人们为目标奋斗,他们中既有运动员又有非运动员。洛奇是当地一名贫穷的拳击手,因与世界重量级冠军阿波罗·祈利比试而崭露头角。由于祈利的严格训练和相对无情,洛奇成了第一个与他打上15回合的挑战者。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

公众宗教研究机构与宗教新闻通讯社联合开展的这项调查显示,不同政治派别和不同宗教信仰的人们对于恶劣天气的观念存在分歧,今年已经发生了多起严重的高温和干旱灾害。
陈女士说:“所有这些搜索项综合反映了2010年的许多方面,还反映了这一年政治和技术领域的变革。”

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

“My manifesto with Summly was to get our technology into as many users’ hands as possible,” Mr D’Aloisio said, pointing to Yahoo’s hundreds of millions of users. “With Yahoo’s reputation as a content portal, we have an opportunity to fundamentally change the way content is consumed.”
Crucially, they note, instability and conflict around the world could continue to drive inflation and affect the costs of living within certain cities.
‘I Could Not Forget What Happened to Me That Night With Him’

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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全球收入最高的女星排行榜4-10位:
adj. 浪漫的

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