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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

毫不奇怪,信贷具有“助周期性”。当资产价格一片繁荣时,乐观的贷款机构倾向于发放更多贷款,进而加剧市场的狂欢。当资产价格下跌时,贷款机构会控制风险,有时这种做法会加速下跌。
我是否有从一天当中能抽出时间来给自己?我们都需要一点“自我时间”。每天留出一些时间放松一下,做你喜欢做的事情——阅读、冥想、看电视、烹饪、跟你爱的人共享黄金时光等等。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

余秀华
《静待黎明》

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

相对而言,这一增幅超过城市居民同期平均薪资涨幅(17.4%)。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Mrs. May’s government proposed a rule that would publicly shame employers who hired foreign workers. And her first major speech was full of barbs directed against multiculturalism, including a jab against people who claimed to be “citizens of the world,” whom she called “citizens of nowhere.”

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Elspeth Cheung, head of BrandZ valuation at Millward Brown, says: “The top 10 used to be dominated by consumer goods. This year, it’s technology.”
虽然这个心脏太虚弱,不能真的输送血液,但是这种细胞组织在修复受伤的心脏肌肉方面具有巨大潜力。
foundation
optimistic

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

虽然考辛斯喜怒无常的性格和高使用率确实是个麻烦,但是仍然有很多理由做出这个交易:
“Policymakers around the world are cognisant of the impact the Fed decision will have and are worried, which makes us worried,” said Simon Lue-Fong, head of global emerging debt at Pictet Asset Management. “People are saying the decision is priced in but seeing as no one knows exactly what will happen how can that possibly be true.”
当年的荷兰金融市场固然没有今天的任何科技,但他们的很多做法都和今天的交易员一样。投资者们买入证券,有时会用买入的股票质押获得贷款。用今天的话说,他们基于保证金买入股票。贷款机构为了自身安全,会要求一个超出贷款金额一定百分比的“折幅”,质押现金或证券。如果证券价格下跌超过一定幅度,贷款机构会要求投资者交出更多资金,与“折幅”保持一致。如果投资者拿不出追加保证金,贷款机构有权将证券平仓,收回贷款额。
摩根大通公司下滑至第4名,其总综合得分位居中国农业银行之后。去年名列前10强的两家欧企——荷兰皇家壳牌和汇丰控股,今年仅分别排名11名和14名。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

After Zhou contaminated the water, one of Zhou's classmates surnamed Tang noticed that the water coming out of the dispenser was milky and had a pungent scent.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

许多人在学习小组中受益良多。你得有条有理地进行,不能拖延时间。你要将学习的内容彻底消化,并能够向别人复述出来。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 租房市场异动,源于市场失衡
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

optimistic
戴假牙的角色

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

在佛罗里达州博卡拉顿林恩大学的辩论,在外交政策和安全上奥巴马有一个固有的优势。作为总统,能接触到情报分析员、外交官和将军的每日简报,他能更好的概括,好像在上半场的辩论中他支配着罗姆尼。
10月,政府宣布准备终结数十年之久的“独生子女政策”。此项政策限制了已婚夫妇的孩子人数。新规定要到明年才会生效。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 智能涂料市场2020年将达58亿美元
Open Access Review Article

Diagnostic technologies for COVID-19: a review

High and rising US rates may quickly become drivers of EM crises: such conditions may lead to higher borrowing costs in EMs, along with capital outflows and an unwillingness by the financial sector to take risks.
Amazon founder Jeff Bezos rose to No. 3 on the list for the first time, thanks to the jump in in Amazon shares, which boosted his net worth to $72.8 billion.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

在如今的江苏省境内的贵族古墓里找到的。
Having reached the current stage of development, China can now advance only through reform and innovation. We have the largest quality workforce as well as the largest pool of scientists, engineers and professionals in the world, and their potential for innovation is truly tremendous.
艾丽斯·斯瓦策尔(Alice Schwarzer)
伯利兹城最富盛名的旅游胜地莫过于巨大的水下天坑--蓝色巨洞以及玛雅遗址。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

n. 流通,循环,发行量,消息传播

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Lawrence Yun, the trade group's chief economist, expects the average 30-year fixed-rate mortgage to hit 5.5% at year-end, up from 4.5% late last year and 3.5% in the first half of 2013. That's a sharp runup in a short period of time, one that could harm affordability and spook even more buyers.
“He’s had more of a sense of swagger and confidence” in recent months, says Jan Dawson of Jackdaw Research.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

美国上市交易相比2016年(多年来最疲弱的年份之一)出现起色。根据Dealogic的统计,今年迄今已有112笔IPO得到定价,而去年这个时候只有63笔。发行金额翻了一番多,达到316亿美元。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Much joy to you in the up coming year. May the warmest wishes, happy thoughts and friendly greetings come at New Year and stay with you all the year through.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

201401/272266.shtml重点单词
Though Hand was British Petroleum's SVP of Global Brand, Marketing and Innovation, for several years, she's on a much more environmentally friendly mission today. Project Frog aims to revamp the construction industry with simple-to-build spaces (they takes days, rather than months to construct) that consume about 50% less energy than traditional buildings for sectors like education and healthcare. Hand's plan seems to be working: revenue is expected to more than double this year.
当晚的最大赢家可能还要属主持人蒂娜?费和埃米?珀勒,这是两人第二次搭档主持金球奖颁奖典礼,且她们今年表现丝毫不逊去年,创下了1,970万观众的六年来最高收视率。金球奖颁奖典礼由好莱坞外国记者协会(Hollywood Foreign Press Association)举办,举办地点位于加利福尼亚州贝弗利山庄的贝弗利山希尔顿酒店(Beverly Hills Hilton)。
6.微型人脑

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

His parents only realised what was going on when the bank called them to let them know about the charges.
一个由BuzzFeed News(译者注:类似今日头条的新闻搜集网站)所做的分析揭示了本年度Facebook上流传最广的50条假新闻。他们加起来大约有2150万次的点赞、评论及分享。在这些新闻里,23条和美国政治相关,2条关于女人用她们的阴道作为谋杀用的凶器,还有1条关于一个小丑娃娃其实一直都是个真人。
TAXES: Approximately $16,866 in 2014
n. 温室,暖房
The city offers excitement beyond your expectations, with grand churches, a richly varied number of museums, a growing modern-art scene and streets that come alive with summer festivals.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

HEC Paris and London Business School have tightened their grip on the top of the Financial Times rankings of pre-experience and post-experience Masters in Finance programmes respectively, having dominated the finance rankings since they were first published in 2011.
随着《喜羊羊与灰太狼》大电影第二部《喜羊羊与灰太狼之虎虎生威》的上映,这部空前火爆的国产动画再度成为众人关注的焦点。你知道怎么用英文介绍《喜羊羊与灰太狼》么?I

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

On Turkey, which recently shot down a Russian warplane, Putin said he sees no possibility of overcoming the strained ties with the current Turkish leadership. He said he was shocked to see that Turkey hadn't tried to explain its action but turned to help from NATO instead.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

多数天主教徒(60%)和非福音派白人新教徒(65%)表示,他们相信飓风和洪灾等自然灾害是气候变化所致。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

4. Adidas. Brand love: 35% / Rank 25
Taylor Swift has been named the most charitable celebrity of 2012.
A record 27,817 civil service jobs are being offered this year by central government departments and subsidiaries.
Mr Lam predicts that any recovery in the market will rely on appetite from cash-rich companies from mainland China, with foreign investors restricting their investments to real estate investment trusts or stocks exposed to developers, rather than actual property.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

这个12岁的女孩已经成为了在Instagram拥有300万粉丝的超级巨星,她和流行歌手希雅(Sia)合作的MV在YouTube上点击量超过10亿。
All kinds of companies say they plan to add senior systems analysts, whose base pay is projected to rise 5% over this year's levels, to as high as $85,500; financial analysts, whose salaries will start at $81,500 at large companies, 4.8% more than in 2010; and experienced administrative assistants, at starting salaries of up to $41,750, a 3.1% increase.
上海实施新措施一年以来,受理外籍人士及其家属永久居留申请同比增长6倍。
授完奖,在他致谢他的粉丝和MTV之前,他兴奋地说到”首先,我想说我不确定我怎么能得到这个奖,因为我已经好几年没有出过唱片了,但是我得奖了。”另外,Kendrick Lamar获得了最佳录影带奖,尽管这位说唱歌手无法到场,而是他通过视频感谢了他的粉丝。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

其他两家手机制造商OPPO和vivo的增长率都超过了100%,在2016年分别出货9940万台和7730万台。
The Meyerowitz Stories

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 东鹏赴港上市融资或超11亿
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Indeed, everyone from Jennifer Garner, to January Jones and Kylie Jenner have been photographed as they pick out their most spook-worthy pumpkins in time to send October out with a thrill.
6. “Taxi”(Jafar Panahi)
It was last above 50 - the threshold separating contraction from expansion - in February.
在海外工作过至少6个月的女性少于男性(比例分别为42%和52%),但动机完全一样:加强管理能力、打造自己的人脉以及提高薪资。
我们再来看看名单里一些其他的亮点:

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

A report from the ministry showed that employers recruited 5.2 million workers through public employment service agencies in the first quarter, dropping 229,000, or 4.5 percent, from the previous year.
Whatever the underlying cause, last year’s extreme warmth in the West meant that Alaska, Arizona, California and Nevada all set temperature records. Some parts of California essentially had no winter last year, with temperatures sometimes running 10 to 15 degrees above normal for the season. The temperature in Anchorage, Alaska’s largest city, never fell below zero in 2014, the first time that has happened in 101 years of record-keeping for the city.
n. 小麦,小麦色

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

报告称,北上广深等一线城市居民承受着较大的经济压力;而四线及以下城市的工作机会较少,人脉在生活的各个方面都起着重要作用。
n.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 海福乐五金携手AIM打造异动空间
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

vt. 安慰,使
I wish you a happy New Year. All affection and best wish
排名:第三

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

图表二显示的是实际联邦基金利率(计入通胀因素后)和实际自然利率。可以再次看到,当联邦基金利率高于自然利率时,新兴市场危机更为常见。
China's consumer price index (CPI), a main gauge of inflation, rose by 1.6% in 2017, lower than the yearly control target of 3%, the National Bureau of Statistics (NBS) said on its website.
GM is addicted to hefty sales incentives to move the cars and new CEO Ed Whitacre knows it. In 2010, he will slash incentives and end up abandoning GM's 20% U.S. market share target to find profitability. The search will prove elusive.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

One of the more notorious incidents was when Zhu Ling, a student at the prestigious Tsinghua University, was paralyzed when her roommate allegedly poisoned her with thallium in 1994.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

伊丽莎白?泰勒和理查德?伯顿的爱情之

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Piano and ballet performance “On My Fingertips And Toes” (Lang Lang and Hou Honglan)
adj. 传统的

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

According to local media, the gang, based in Nanning, the capital city of south China's Guangxi Zhuang autonomous region, was able to make up to 16,000 yuan (£1,750) profit on every tonne of the putrid meat, by injecting it with chemicals, increasing its weight by 50 per cent.
2016年国家公务员考试报名人数已经超过去年,仅周二一天,符合考试条件的报考人员就达到13.2万人以上,这是单日报考人数最高的一天。
What? Hasn't his firm made enough money off Bernanke's cheap money printing? So he's blaming 'lower growth on fiscal austerity, ' even as Bernanke keeps blowing up the Fed's balance-sheet bubble by trillions under the delusion he's America's savior because our dysfunctional Congress failed?
夏洛特·艾玛·艾奇逊《1号天使》

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

她说:“所有监管机构都在考虑这么做,提高透明度始终是可喜的。但能否做到则是另一回事。监管机构谈论提高透明度并降低费用,但在立法方面没什么进展。”
The Cnzz.com report also discusses the problem of the 'free-to-play' business model that's prevalent in China's online game sector. While many games companies in the U.S., for example, charge subscription fees, most Chinese games utilize the free-to-play model, which allows players to try out a game without paying. The longer players stay in the game, the more likely they will be to pay for in-game items to move up into higher levels of play. But that also means that people who spend the most money are the best performers.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

印度国家板球队
节目13 歌曲《嫦娥》,李玉刚 景海鹏 刘旺 刘洋

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

全球肥胖率上升的前因后果。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

3. Not starting your own business
以下是专家提供的,明年的生存和发展建议:
印度总理纳伦德拉莫迪(Narendra Modi)会尝试更多非正统的经济试验吗?
3.贫穷

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 承租人诉大兴区政府 区长应诉
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

adj. 突出的,显著的,未支付的
WhatsApp had been particularly ad-averse before its sale to Facebook. CEO Jan Koum kept a note from co-founder Brian Acton taped to his desk to remind him of the company’s core values. It read: “No Ads! No Games! No Gimmicks!”

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

“My manifesto with Summly was to get our technology into as many users’ hands as possible,” Mr D’Aloisio said, pointing to Yahoo’s hundreds of millions of users. “With Yahoo’s reputation as a content portal, we have an opportunity to fundamentally change the way content is consumed.”
Germanyjust hung four onPortugal. It was a bit of a shocking result, at least from the perspective that most observers expectedPortugalto put up a bit more fight. But it was another relatively high-scoring game at World Cup 2014? Not surprising at all.
三线城市居民的经济压力和人际关系压力相对较小,且拥有更好的社会环境、自然环境和基础设施。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

除了要符合质量标准之外,进口商品还必须按中国规定正确标注。
先是“非典”,接下来是全球范围的H5N1以及H1N1流感大爆发。全球化也无能为力。现在地球实际就是一个小村庄,这也使得病毒在几小时内,就能轻而易举地从北京传播到波士顿。2010我们是否会再次遭遇另一场“甲流”?
Despite the breakthrough, Jack Ma, chairman of Alibaba Group, said there was no need for human beings to fear machines.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 装修建材抬高身价
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

8.俄罗斯
36岁的阿德里亚娜·利马排在第四位,其收入为1050万美元,初为人母的罗西·亨廷顿-怀特利(950万美元)与25岁的卡莉·克劳斯(900万美元)分别位列榜单的第六位和第七位。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

“尽管我本质上是一名工程师和分析人员,但迄今为止我所做过的最重要的决定都与此无关,它们永远是基于直觉,”他去年在曾就读MBA的杜克大学(Duke University)对一名采访者表示。
英国
cap容纳+acity表名词,“有…倾向”→容量;能力

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Apple CEO Tim Cook
'In total I've spent about £5,000 in three months on my three girls. One dress cost me $200 and she only wore it twice before she grew out if it - but I don't intend to lower my spending.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

墓地主人的身份依然是个迷。这座墓地曾经被盗过,而且墓地中没有任何的文字记录来表明这些死者的名字以及他们的职位。
明星们的私家飞机刚停稳,“老爹身材”一词便在互联网上走红。男性微胖的身材成为潮流,荧幕上不少这样的例子。法新社(AFP)Deborah Cole(黛博拉?科尔)写道:“杰拉尔?德帕迪约(Gerard Depardieu)在《爱之谷》中的形象便是“大汗淋漓、气喘吁吁地打着赤膊”, 华金?菲尼克斯 (Joaquin Phoenix)在 伍迪?艾伦(Woody Allen)的新片《非理性的人》(Irrational Man)中也露出了他那胖胖的肚子。科林?法瑞尔(Colin Farrell)出席《龙虾》(The Lobster)的首映红毯时,看起来如往常一般衣冠楚楚,然而在剧中他却大腹便便。为了给荒诞主义者欧格斯?兰斯莫斯(Yorgos Lanthimos)的黑色喜剧中的孤独主角增肥,法瑞尔大量进食高热量食品,其中包括融化了的冰淇淋。他告诉《好莱坞报道》(Hollywood Reporter),“在早晨10点享用2个芝士汉堡、薯条和可乐可不那么有趣,”他补充道,“不过我喜欢芝士汉堡。”
6、所有扮演邦德的演员都是高个子,这不是巧合。身高1.6的男人每年要多赚175000英镑才能与身高1.8的男人媲美。很多人欣赏丹尼尔在《皇家赌场》的魁梧身材。科学研究证明,肌肉男有更多的一夜情,从一个男人的臂围可以看出他与多少女人风流过,魁梧身段就意味着他是个不错的情人。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

adj. 荒谬的,可笑的

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

还记得《类人猿行动》吗.这是一部被众人忽略的2016年早些时候的电影,由杰米.多南和斯里安.墨菲担任主演,讲述了对希特勒身边的三把手、党卫队将军莱因哈德.海德里希进行的一次失败暗杀。《行动代号:猿人》也尝试讲述这一故事,杰克.莱诺和奥康奈尔将在片中饰演密谋的士兵,而罗莎曼德.派克和米娅.华希科沃斯卡是他们片中的感情对象,杰森.克拉科则饰演他们的刺杀目标。
物理学界这一开拓性的发现已经点燃科学研究的星星之火,而他们的这项研究发展为前沿科技,也不过是时间早晚的事罢了,就像100年前我们无法想象今天的激光和电脑芯片那样,美国物理学会候选会长劳拉?H?格林在接受《纽约时报》采访时表示。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 住宅用地供应1000公顷
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

“We have resolved this matter and will move forward to build on the important actions Honda has already taken to address our past shortcomings in early warning reporting,” said RickSchostek, Honda executive vice president, in a statement. “We continue to fully cooperate with NHTSA to achieve greater transparency and to further enhance our reporting practices.”
Enthusiastic supporters of the idea of a “universal basic income” for all citizens, meanwhile, will look to Finland where a trial is now well under way. In France, Emmanuel Macron will try to tread a delicate line in 2018 as he reforms the labour market, hoping to inject flexibility without increasing insecurity or incensing the unions.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 家具市场定制热2016年持续升温
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

保障房倡导者们则担心,如果重新区划做得不认真,那么居民社区或将迅速士绅化。“看看威廉斯堡(Williamsburg)发生了什么吧,”城市正义中心(Urban Justice Center)的社区开发项目负责人哈维·艾普斯坦(Harvey Epstein)说,他指的是房价上涨,“我不明白,它怎么就不可能发生在东纽约、布朗克斯或者法拉盛呢。”
上班迟到,休息后又迟回工作岗位表现出来的是一种傲慢、随便的工作态度。 因此,快速或者甚至是稍微提前一点进入工作状态说明你有时间观念,你确实很在乎工作和别人时间。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Video footage recorded by the RSPCA shows the house littered with mess, including animal faeces.
According to Feng Zhenglin, head of the Civil Aviation Administration of China, weather accounted for 56.8% of flight delays in 2016, up from 29.5% the previous year.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Rossello also has pledged to work closely with a federal control board that U.S. Congress created last year to oversee Puerto Rico’s finances, and he has said he supports negotiations with creditors to help restructure a nearly $70 billion public debt.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

May the New Year be a time of laughter and real enjoyment for you. Best wishes.愿新年不仅是你欢笑的时刻,更是你欣喜的日子。祝福你。
Klay Thompson added 19 points and Andrew Bogut scored 13 for the Warriors, off to the best start by an NBA team since Dallas won its first 14 games in 2002-03. Golden State needs three wins to equal the league record of 15-0, held by the 1948-49 Washington Capitols and 1993-94 Houston Rockets.
n. 示范,实证,表达,集会
Along with having her artwork featured on Google's homepage, Zhang wins a $30,000 college scholarship. In addition, her school will receive a $50,000 Google for Education technology grant, and the company is donating $20,000 in her name to a charity dedicated to bringing clean water to schools in Bangladesh.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Take targeted and powerful measures to strengthen areas of weakness.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 2015淋浴房十大品牌最新排行榜
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

关注规模较小和私营制造企业的财新制造业PMI下降,而主要关注规模较大和国有企业的官方制造业PMI指数同期出现上升。这种分歧可能表明,比起规模较大和国营的企业,较小的企业受污染限制和其他监管收紧的冲击更为严重。前者还享受国有银行的优惠待遇。
Please accept my season\'s greetings.
自工业革命以来,全球气温已经上升了0.8摄氏度。虽然去年1摄氏度的升温不太可能在今后每年都出现,但科学家表示由于厄尔尼诺事件的持续,2016年可能又将是一个极端炎热的年份。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

1.Shailene Woodley
This founding father argued that the college would both guard against the desire in foreign powers to gain an improper ascendant in our councils and ensure the office of President will never fall to the lot of any man who is not in an eminent degree endowed with the requisite qualifications.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 八大关键词带你读懂2015家居市场
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

It adds up to a pointed reminder that Her Royal Swiftness can reclaim her place at pop's cutting edge whenever she feels like it.
勒布朗·詹姆斯

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

vt. 编预算,为 ... 做预算

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

受此启发,研究者和科学家们都致力于研发体积小却意义重大的科技成果。
Also important to EMBA entrepreneurs was the support of their school and alumni network. About three-quarters of entrepreneurs thought that both the school and their alumni network were helpful or very helpful when setting up their company. “Alumni support was key to getting the idea vetted and getting the right contacts needed for the business”, said one.
"When the actual dependency ratio of pension insurance gets down to three to one, the payment cannot be lower than 17 percent. If it drops to two to one ratio, it means that everyone is going to pay 25 percent. The financial burden gets heavier when the dependency ratio gets lower. The restructuring of pension system must be finalized in two years." Yang said.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

在许多情况下,这种做法已经渐渐从政界边缘进入主流。比如说,英国的执政党保守党立场是中间偏右,它曾经推进英国脱欧,公投之后,新的保守党首相特丽莎?梅(Theresa May)表现出对白人身份政治的同情。
数年来,莎尔玛·海雅克和格温妮丝·帕特洛都是性侵的受害者,麦高恩表示,她明白特朗普的支持者都憎恨好莱坞,因为他们的自由主义都是假的。
献上节日的问候与祝福,愿你拥有一个充满生机和欢乐的新年。
7、人民币贬值

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 居然之家电商总经理汪小康离职
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

“One person had his wife call to tell his boss he was not coming back.”
*最佳真人秀主持:鲁保罗?查尔斯(RuPaul Charles),《鲁保罗变装皇后秀》(RuPaul’s Drag Race, Logo)

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

“Insead enormously boosted our intercultural experience,” said one alumni survey respondent from Switzerland. “It is a place to learn global culture better than anywhere else.”
去年一系列洪灾袭击了世界各国,英国也包括在内。去年12月英国经历了1910年开始记录以来雨水最多的月份。
清华大学是国内表现最好的大学,有三项学科的排名进入全球前10。北京大学则是有两项学科排名挤入前十。就清华大学而言,建筑/建成环境和土木/结构工程学均排名第8,材料科学排名第10。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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9. Putting Yourself in Someone Else's Shoes Improves Memory
这些弊端是很现实的,但是也有很多方法来回避它们。比如说,你可以利用你的谋生工作向雇主展示你努力工作的诚意。并且你也可以在工作之余继续找其他的好工作。

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